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Histopathological picture of a hyperplastic polyp. The arrow highlights mucin vesicles. Hematoxylin–eosin, 200×.

Histopathological picture of an SSL. L- and T-shaped crypts are highlighted by arrows. Hematoxylin–eosin, 40×.

Histopathological picture of an SSL with dysplasia (red arrow) and a pseudo-invasive pattern (black arrow). Hematoxylin–eosin, 40×.

Histopathological picture of a TSA. Penicillate nuclei are indicated in the inset by an arrow. Hematoxylin–eosin, 20×.

Histopathologic features of serrated polyps. (A) Hyperplastic polyp: straight crypts from the surface to the muscularis propria. (B) SSL: deep crypt dilation/serration with boot-, L-, or inverted-T-shaped bases, and crypt herniation through the muscularis propria. (C) TSA: pencillate nuclei, eosinophilic cytoplasm, and ectopic crypts.

Endoscopic appearance of serrated polyps. (A) Hyperplastic polyp: pale, smooth, and flat. (B) SSL: pale and flat with irregular borders, commonly covered by a mucous cap.