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CLASSIFICATION
Classification
Paris classification (superficial morphology)
Endoscopic Type 0 morphology of superficial neoplasia (mucosa to submucosa) in the esophagus, stomach, and colorectum: protruding (0-I), flat (0-II), and excavated (0-III). 0-Isp is not in the 2003/2005 Paris table.
Classification overview
0-I · Protruding
0-Ip · Pedunculated
0-Is · Sessile
0-II · Nonprotruding and nonexcavated
0-IIa · Slightly elevated
0-IIb · Completely flat
0-IIc · Slightly depressed
0-IIc+IIa · Depressed with elevated rim
0-IIa+IIc · Elevated with central depression
0-III · Excavated family
0-III · Excavated (ulcer)
0-IIc+III · Depressed with central ulcer
0-III+IIc · Ulcer with depressed margin
Protruding
0-Ip
Pedunculated
GI Calc, Not original, CC BY
Category
Protruding
Morphology
Pedunculated
Cut-off
Protruding vs slightly elevated: 2.5 mm (columnar epithelium; closed biopsy forceps) or 1.2 mm (esophageal squamous epithelium)
0-Is
Sessile
GI Calc, Not original, CC BY
Category
Protruding
Morphology
Sessile
Cut-off
Elevation from the adjacent mucosa is at least 2.5 mm in columnar epithelium (1.2 mm in the esophagus)
Note: Sessile colorectal lesions have a relatively high SM-invasion rate (2005 Table 4: 34% for colorectal 0-Is).
Nonprotruding
0-IIa
Slightly elevated
GI Calc, Not original, CC BY
Category
Nonprotruding and nonexcavated
Morphology
Slightly elevated
Cut-off
Elevation less than 2.5 mm from the adjacent mucosa in columnar epithelium (less than 1.2 mm in the esophagus)
0-IIb
Completely flat
GI Calc, Not original, CC BY
Category
Nonprotruding and nonexcavated
Morphology
Completely flat
Note: Very rare in the colorectum.
0-IIc
Slightly depressed
GI Calc, Not original, CC BY
Category
Nonprotruding and nonexcavated
Morphology
Slightly depressed
Cut-off
Depression less deep than 1.2 mm in columnar epithelium (0.5 mm in esophageal squamous epithelium). Deeper lesions are excavated (0-III).
Note: Depressed lesions have a high SM-invasion risk (2005 Table 4: 61% for colorectal 0-IIc).
0-IIc+IIa
Depressed + elevated rim
GI Calc, Not original, CC BY
Category
Elevated and depressed types
Morphology
Most of the surface is depressed; elevation is present in a segment of the lesion at the periphery
0-IIa+IIc
Elevated + central depression
GI Calc, Not original, CC BY
GI Calc, Not original, CC BY
Category
Elevated and depressed types
Morphology
There is a central depression in a globally elevated lesion. The central depression is surrounded by an elevated ring.
Note
When the level of the depression is higher than the mucosa adjacent to the lesion, it is a relatively depressed lesion.
Excavated
0-III
Excavated (ulcer)
GI Calc, Not original, CC BY
Category
Excavated
Morphology
Ulcer
Note: Almost never seen in the colorectum.
0-IIc+III
Depressed + central ulcer
GI Calc, Not original, CC BY
Category
Excavated and depressed types
Morphology
A depressed lesion with a central ulcer
0-III+IIc
Ulcer + depressed margin
GI Calc, Not original, CC BY
Category
Excavated and depressed types
Morphology
An ulcer with short depressed margins